Certified Hospice and Palliative Assistant (CHPNA) Practice Test

What is a common adverse effect observed with the use of high-dose opioids?

1. Severe headaches

2. Constipation due to slowed gastrointestinal motility

3. Increased energy levels

4. Improved sleep patterns

The correct answer is: Constipation due to slowed gastrointestinal motility

The correct answer highlights a well-known side effect associated with opioid use, particularly at high doses. Opioids work by binding to specific receptors in the body to reduce pain, but one of their effects is to slow down gastrointestinal motility. This means that the movement of the digestive tract is decreased, leading to constipation. Constipation is a significant concern for healthcare providers and patients using opioids because it can lead to discomfort and additional health complications if not managed properly. Increased fiber intake, adequate hydration, and sometimes the use of laxatives are common strategies employed to alleviate this side effect. The other options listed do not accurately reflect the typical adverse effects of high-dose opioid administration. Severe headaches may occur from various causes but are not a direct result of high-dose opioid therapy. Similarly, increased energy levels and improved sleep patterns are not associated effects; in fact, opioids can often lead to sedation and fatigue rather than increased activity or better sleep quality.