Certified Hospice and Palliative Assistant (CHPNA) Practice Test

What is one of the body's responses to high levels of opioid metabolites?

1. Increased relaxation

2. Decreased consciousness

3. Myoclonus

4. Improved appetite

The correct answer is: Myoclonus

One of the body's responses to high levels of opioid metabolites is myoclonus, which refers to sudden, involuntary muscle jerks or spasms. This can occur as a side effect of opioid medication, especially in patients who have been on opioids for a prolonged period or those with kidney impairment who may not be able to clear these metabolites effectively. Myoclonus is considered a potentially serious effect because it can indicate toxicity or an adverse reaction to the medication. Additionally, the presence of myoclonus may affect a patient's ability to relax and can potentially lead to further complications if not managed appropriately. Other responses to high levels of opioid metabolites might include changes in mood, cognitive function, and awareness, which could account for the other options. However, the response characterized by involuntary muscle contractions most directly aligns with the definition of myoclonus as a specific and measurable reaction to opioid metabolite levels.